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Wiping out childhood ear infections

Team

January 2021

Optimising a 6-plex tetanus-diphtheria-pertussis fluorescent bead-based immunoassay

Small volume assays are required for large-scale research studies and in particular paediatric trials, where multiple measures are required from a single sample. Fluorescent bead-based technology (Bioplex/Luminex) allows high through-put and simultaneous quantification of multiple analytes in a single test. This technology uses sets of microspheres, each with a unique spectral address that can be coated with a different antigen of interest.

Published research Immunisation Whooping Cough Vaccine Trials Group Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Bacterial Respiratory Infectious Disease Group
March 2020

Panel 8: Vaccines and immunology

Review and highlight of the significant advances made towards vaccine development and understanding of the immunology of otitis media

Published research Infectious Diseases Bacterial Respiratory Infectious Disease Group
March 2020

Panel 4: Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures

Advances in understanding bacterial dynamics in the upper airway microbiome are driving development of microbiota-modifying therapies to prevent or treat disease

Published research Ear Infections Bacterial Respiratory Infectious Disease Group