Wesfarmers Centre of Vaccines & Infectious Diseases
What is an adaptive trial?
Team
Infectious Disease Implementation Research projects
Resources
Extra whooping cough shot to protect your bub
Professor Tom Snelling
Reports and Findings
Acute haemoptysis, fever and abdominal pain in an adolescent from northern Australia
Published research Infectious Disease Implementation Research Infectious Diseases Epidemiology P4 Respiratory Health for Kids Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Skin Health BREATHStatistical analysis plan for the OPTIMUM study: optimising immunisation using mixed schedules, an adaptive randomised controlled trial of a mixed whole-cell/acellular pertussis vaccine schedule
The purpose of this double-blind, randomised, controlled trial is to compare allergic outcomes in children following vaccination with acellular pertussis (aP) antigen (standard of care in Australia) given at 2 months of age versus whole cell pertussis (wP) in the infant vaccine schedule.
Published research Whooping Cough Infectious Disease Implementation Research Vaccine Trials GroupPertussis Disease and Antenatal Vaccine Effectiveness in Australian Children
Population-level studies of severe pertussis extending beyond infancy are sparse, and none in the context of antenatal vaccination. We compared hospitalized pertussis cases from birth to 15 years of age before and after introduction of antenatal immunization.
Published research Immunisation Whooping Cough Infectious Diseases Infectious Disease Implementation Research Infectious Diseases Epidemiology Vaccine Trials GroupStatus epilepticus outcomes among vaccinated and unvaccinated children: A population-based study
To determine the proportion of first status epilepticus cases that are vaccine-proximate and compare clinical outcomes to non-vaccine-proximate cases.
Published research Infectious Disease Implementation Research