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Protecting children against food allergies
What is pneumococcal disease?
Reports and Findings
A Prospective Study Investigating the Impact of Obesity on the Immune Response to the Quadrivalent Influenza Vaccine in Children and Adolescents
Obesity can increase the severity of influenza infection. Data are limited regarding immune responses to influenza vaccination in obese children. We aimed to investigate the impact of obesity on quadrivalent influenza vaccine responses in children.
Published research Influenza Vaccine Trials Group Subsite: Wesfarmers Centre of Vaccines and Infectious DiseasesAustralian Aboriginal Otitis-Prone Children Produce High-Quality Serum IgG to Putative Nontypeable Haemophilus influenzae Vaccine Antigens at Lower Titres Compared to Non-Aboriginal Children
Nontypeable Haemophilus influenzae (NTHi) is the most common bacterial otopathogen associated with otitis media (OM). NTHi persists in biofilms within the middle ears of children with chronic and recurrent OM. Australian Aboriginal children suffer exceptionally high rates of chronic and recurrent OM compared to non-Aboriginal children.
Published research Ear Infections Vaccine Trials Group Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Bacterial Respiratory Infectious Disease GroupSleep Disordered Breathing and Recurrent Tonsillitis Are Associated With Polymicrobial Bacterial Biofilm Infections Suggesting a Role for Anti-Biofilm Therapies
The underlying pathogenesis of pediatric obstructive sleep disordered breathing (SDB) and recurrent tonsillitis (RT) are poorly understood but need to be elucidated to develop less invasive treatment and prevention strategies.
Published research Vaccine Trials Group Airway Epithelial Research Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Bacterial Respiratory Infectious Disease GroupA brief history of MECP2 duplication syndrome: 20-years of clinical understanding
MECP2 duplication syndrome (MDS) is a rare, X-linked, neurodevelopmental disorder caused by a duplication of the methyl-CpG-binding protein 2 (MECP2) gene-a gene in which loss-of-function mutations lead to Rett syndrome (RTT). MDS has an estimated live birth prevalence in males of 1/150,000.
Published research Child Disability Vaccine Trials Group Children's Lung Health Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Child disability