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Protecting children against food allergies
What is pneumococcal disease?
Reports and Findings
A phase III, multicenter, randomized, double-blind, active comparator-controlled study to evaluate the safety, tolerability, and immunogenicity of catch-up vaccination regimens of V114, a 15-valent pneumococcal conjugate vaccine(PNEU-PLAN)
Despite widespread use of pneumococcal conjugate vaccines (PCVs) in children, morbidity and mortality caused by pneumococcal disease (PD) remain high. In addition, many children do not complete their PCV course on schedule. V114 is a 15-valent PCV that contains two epidemiologically important serotypes, 22F and 33F, in addition to the 13 serotypes present in PCV13, the licensed 13-valent PCV.
Published research Immunisation Vaccine Trials Group Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Immune systemEarly onset of otitis media is a strong predictor of subsequent disease in urban Aboriginal infants: Djaalinj Waakinj cohort study
Australian Aboriginal and/or Torres Strait Islander children in rural/remote areas suffer high rates of persistent otitis media (OM) from early infancy. We aimed to determine the proportion of Aboriginal infants living in an urban area who have OM and investigate associated risk factors.
Published research Ear Infections Aboriginal Health Child Disability Ear Health Vaccine Trials Group Subsite: Wesfarmers Centre of Vaccines and Infectious DiseasesEstimating the excess burden of pertussis disease in Australia within the first year of life, that might have been prevented through timely vaccination
Previous Australian studies have shown that delayed vaccination with each of the three primary doses of diphtheria-tetanus-pertussis-containing vaccines (DTP) is up to 50 % in certain subpopulations. We estimated the excess burden of pertussis that might have been prevented if (i) all primary doses and (ii) each dose was given on time.
Published research Whooping Cough Infectious Diseases Infectious Diseases Epidemiology Vaccine Trials Group Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases