Featured Projects
In partnership with Derbarl Yerrigan Health Service and the Broome Regional Aboriginal Medical Service, we aim to improve Aboriginal lung health by determining for the first time the baseline lung function of Aboriginal Australians.
We hope that through earlier diagnosis and treatment of muscle weakness during sleep, we can prevent future lung failure in children with neuromuscular disorders.
Understanding if ongoing inflammation in the lungs contributes to the poor lung health experienced by some children who were born preterm.
Lung damage in children with CF occurs much earlier than previously thought, and proving this is related to the decline that occurs later will create new paradigms for prevention and treatment.
Many Healthy Lungs
Project
Team
Children's Lung Health projects
Lung damage in children with CF occurs much earlier than previously thought, and proving this is related to the decline that occurs later will create new paradigms for prevention and treatment.
Past Projects
Children's lung health videos
AREST CF
Reports and Findings
Ventilatory response and stability of oxygen saturation during a hypoxic challenge in very preterm infants
Preterm infants have immature control of breathing and impaired pulmonary gas exchange. We hypothesized that infants with bronchopulmonary dysplasia (BPD) have a blunted ventilatory response and peripheral oxygen saturation (SpO2 ) instability during a hypoxic challenge.
Published research Children's Lung Health Neonatal Cardiorespiratory Health Subsite: Walyan Pre-term birthHost-dependent resistance of Group A Streptococcus to sulfamethoxazole mediated by a horizontally-acquired reduced folate transporter
Described antimicrobial resistance mechanisms enable bacteria to avoid the direct effects of antibiotics and can be monitored by in vitro susceptibility testing and genetic methods. Here we describe a mechanism of sulfamethoxazole resistance that requires a host metabolite for activity.
Published research Children's Lung Health Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Subsite: END RHD Invasive Streptococcus A Disease Healthy Skin and ARF Prevention BREATH Strep A Pathogenesis and DiagnosticsThe ventilatory response to hypoxia is blunted in some preterm infants during the second year of life
Preterm birth and subsequent neonatal ventilatory treatment disrupts development of the hypoxic ventilatory response (HVR). An attenuated HVR has been identified in preterm neonates, however it is unknown whether the attenuation persists into the second year of life.
Published research Children's Lung Health Neonatal Infection and Immunity Pre-term birthFactors influencing participation in home, school, and community settings by children and adolescents with neuromuscular disorders: A qualitative descriptive study
This study explored how children and adolescents with a neuromuscular disorder (NMD) and their parents experienced barriers and enablers to the child's participation.
Published research Early Childhood Development Child Disability Children's Lung Health