Featured Projects
In partnership with Derbarl Yerrigan Health Service and the Broome Regional Aboriginal Medical Service, we aim to improve Aboriginal lung health by determining for the first time the baseline lung function of Aboriginal Australians.
We hope that through earlier diagnosis and treatment of muscle weakness during sleep, we can prevent future lung failure in children with neuromuscular disorders.
Understanding if ongoing inflammation in the lungs contributes to the poor lung health experienced by some children who were born preterm.
Lung damage in children with CF occurs much earlier than previously thought, and proving this is related to the decline that occurs later will create new paradigms for prevention and treatment.
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Many Healthy Lungs
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Children's Lung Health projects
Lung damage in children with CF occurs much earlier than previously thought, and proving this is related to the decline that occurs later will create new paradigms for prevention and treatment.
Understanding if ongoing inflammation in the lungs contributes to the poor lung health experienced by some children who were born preterm.
Children's lung health videos
AREST CF
Reports and Findings
Official ERS technical standard: Global Lung Function Initiative reference values for static lung volumes in individuals of European ancestry
Measurement of lung volumes across the life course is critical to the diagnosis and management of lung disease. The aim of the study was to use the Global Lung Function Initiative methodology to develop all-age multi-ethnic reference equations for lung volume indices determined using body plethysmography and gas dilution techniques.
Published research Children's Lung Health Subsite: WalyanVariants associated with HHIP expression have sex-differential effects on lung function
Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females.
Published research Children's Lung HealthPulmonary Gas Exchange Improves over the First Year in Preterm Infants with and without Bronchopulmonary Dysplasia
Right shift of the peripheral oxyhaemoglobin saturation (SpO2) versus inspired oxygen pressure (PIO2) curve is a sensitive marker of pulmonary gas exchange. The aim of this study was to assess the impact of prematurity and bronchopulmonary dysplasia (BPD) on gas exchange and right-to-left shunt in the neonatal period, and its evolution over the first year of life.
Published research Early Childhood Development Children's Lung Health Neonatal Cardiorespiratory HealthLung abnormalities do not influence aerobic capacity in school children born preterm
Children born preterm have impaired lung function and altered lung structure. However, there are conflicting reports on how preterm birth impacts aerobic exercise capacity in childhood. We aimed to investigate how neonatal history and a diagnosis of bronchopulmonary dysplasia (BPD) impact the relationship between function and structure of the lung, and aerobic capacity in school-aged children born very preterm.
Published research Early Childhood Development Children's Lung Health Children’s Respiratory Science