The new sarcoma research team
Related Links
Cancer Centre
Team
Sarcoma Translational Research projects
Reports and Findings
Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma
Mesothelioma is characterised by its aggressive invasive behaviour, affecting the surrounding tissues of the pleura or peritoneum. We compared an invasive pleural model with a non-invasive subcutaneous model of mesothelioma and performed transcriptomic analyses on the tumour samples.
Children's Cancers Published research Systems Immunology Airway Epithelial Research Sarcoma Translational ResearchStimulation of alpha-1 adrenoceptors may intensify cutaneous inflammation in complex regional pain syndrome
Alpha-1 adrenoceptors are overexpressed in the epidermis of a subgroup of patients with complex regional pain syndrome. Activating α 1 -adrenoceptors in epidermal cells increases production of the proinflammatory cytokine interleukin-6, a mediator of inflammation.
Published research Sarcoma Translational ResearchFuzzy model for quantitative assessment of the epidemic risk of African Swine Fever within Australia
African Swine Fever (ASF) has spread rapidly across different continents since 2007 and caused huge biosecurity threats and economic losses. Establishing an effective risk assessment model is of great importance for ASF prevention, especially for those ASF-free countries such as Australia.
Published research Infectious Diseases Sarcoma Translational ResearchGlutamine Deprivation Synergizes the Anticancer Effects of Cold Atmospheric Plasma on Esophageal Cancer Cells
Esophageal cancer is a highly aggressive malignancy with a low response to standard anti-cancer therapies. There is an unmet need to develop new therapeutic strategies to improve the clinical outcomes of current treatments. Cold atmospheric plasma (CAP) is a promising approach for cancer treatment, and has displayed anticancer efficacy in multiple preclinical models. Recent studies have shown that the efficacy of CAP is positively correlated with intracellular reactive oxygen species (ROS) levels.
Children's Cancers Published research Sarcoma Translational Research