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Reports and Findings
Performance of the Autism Observation Scale for Infants with community-ascertained infants showing early signs of autism
We investigated whether a commonly used research assessment - the Autism Observation Scale for Infants (AOSI) - accurately measures autism behaviours among infants showing early signs of autism identified within the community. The AOSI is often included in studies tracking the development of infants at increased likelihood of autism, such as the infant siblings of diagnosed children. However, the suitability of this measure has not previously been tested with community-referred infants.
Autism Spectrum Disorders Published research Autism Research Subsite: Autism & Related DisordersTemperament in individuals with Autism Spectrum Disorder: A systematic review
The study of temperament in Autism Spectrum Disorder (ASD) has the potential to provide insight regarding variability in the onset, nature, and course of both core and co-morbid symptoms. The aim of this systematic review was to integrate existing findings concerning temperament in the context of ASD. Searches of Medline, PsychInfo and Scopus databases identified 64 relevant studies. As a group, children and adolescents with ASD appear to be temperamentally different from both typically developing and other clinical non-ASD groups, characterized by higher negative affectivity, lower surgency, and lower effortful control at a higher-order level.
Autism Spectrum Disorders Published research Autism Research Subsite: Autism & Related DisordersFunctioning, participation, and quality of life in children with intellectual disability: an observational study
To investigate associations between functioning, community participation, and quality of life (QoL) and identify whether participation mediates the effects of functioning on QoL.
Autism Spectrum Disorders Published research Academic Biostatistics Child Disability Autism ResearchDevelopmental vitamin D deficiency increases foetal exposure to testosterone
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders which are more common in males. The 'prenatal sex steroid' hypothesis links excessive sex-steroid exposure during foetal life with the behavioural differences observed in ASD. However, the reason why sex steroid exposure may be excessive remains unclear. Epidemiological studies have identified several environmental risk factors associated with ASD, including developmental vitamin D (DVD) deficiency.
Autism Spectrum Disorders Published research Vitamin D and Sunlight Autism Research Subsite: Autism & Related Disorders