Infectious Diseases Physician, Deputy Director of the Wesfarmers Centre of Vaccines and Infectious Diseases
MBBS, DCH, PG DipPID, FRACP, NHMRC Postgraduate Scholarship
Areas of research interest: Staphylococcus aureus, paediatric bloodstream infections, immunisations for children medically-at-risk, central line associated bloodstream infections, infections in the immunocompromised host and other paediatric infectious diseases.
Dr Anita Campbell is a clinician researcher working as a paediatric infectious disease specialist and medical lead of the Stan Perron Immunisation service at Perth Children’s Hospital. Dr Campbell was also recently appointed as a Deputy Director of the Wesfarmers Centre of Vaccines and Infectious Diseases (WCVID), based at Telethon Kids Institute.
Dr Campbell embarked on an NHMRC funded PhD with the WCVID and the University of Western Australia in 2017, leading a multicentre national prospective cohort study on the clinical and microbiological epidemiology of paediatric Staphylococcus aureus bacteraemia.
Dr Campbell also forms representation on the Australian and New Zealand Paediatric Infectious Diseases committee.
As a paediatrician and clinician-researcher in Infectious Diseases, Dr Campbell aims to continue to advocate for child health through harnessing education, innovation and research into evidence-based clinical care.
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Publications
December 2022
Consumer perspectives on simplified, layered consent for a low risk, but complex pragmatic trial
For decades, the research community has called for participant information sheets/consent forms (PICFs) to be improved. Recommendations include simplifying content, reducing length, presenting information in layers and using multimedia. However, there are relatively few studies that have evaluated health consumers' (patients/carers) perspectives on the type and organisation of information, and the level of detail to be included in a PICF to optimise an informed decision to enter a trial.
Published research Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Healthy Skin and ARF PreventionMarch 2022Whole genome sequencing and molecular epidemiology of paediatric Staphylococcus aureus bacteraemia
The role Staphylococcus aureus antimicrobial resistance genes and toxins play in disease severity, management and outcome in childhood is an emerging field requiring further exploration.
Skin Infections Group A Streptococcal & Rheumatic Heart Disease Infectious Diseases Epidemiology Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Invasive Streptococcus A DiseaseFebruary 2022Status epilepticus following vaccination in children aged ≤24 months: A five-year retrospective observational study
Status epilepticus is associated with significant morbidity and mortality. While vaccine-proximate status epilepticus (VP-SE) has rarely been associated with cases of Dravet syndrome, it is not known whether VP-SE differs clinically from non-vaccine proximate status epilepticus (NVP-SE).
Published research Early Childhood Development Immunisation Subsite: Wesfarmers Centre of Vaccines and Infectious DiseasesAugust 2022Urinary tract infections in children: building a causal model-based decision support tool for diagnosis with domain knowledge and prospective data
Diagnosing urinary tract infections (UTIs) in children in the emergency department (ED) is challenging due to the variable clinical presentations and difficulties in obtaining a urine sample free from contamination.
Published research Infectious Disease Implementation Research Infectious Diseases Epidemiology Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Healthy Skin and ARF PreventionMarch 2021Meningococcal serotype W septic arthritis: Case series in children
The epidemiology of invasive meningococcal disease has changed over the last decade and there has been an increase in cases caused by serogroup W135, particularly in Indigenous children. Extra‐meningeal and atypical presentations are associated with serogroup W and may delay diagnosis and therefore appropriate treatment. Public and clinician awareness are essential in facilitating effective new vaccine schedule implementation.
Published research Immunisation Aboriginal Health Infectious Diseases Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Healthy Skin and ARF PreventionMarch 2021Case Report: Neonatal Varicella Acquired From Maternal Zoster
The incidence of neonatal varicella has decreased dramatically since the introduction of the varicella vaccination. Although the varicella zoster virus is often associated with a mild infection, it may cause severe morbidity and mortality, particularly in the neonatal period and immunocompromised hosts. We report a case of neonatal varicella acquired from maternal zoster in a mother on biological immunosuppressive therapy.
Published research Infectious Diseases Infectious Diseases Epidemiology Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Healthy Skin and ARF PreventionSeptember 2021Acute haemoptysis, fever and abdominal pain in an adolescent from northern Australia
Published research Infectious Disease Implementation Research Infectious Diseases Epidemiology P4 Respiratory Health for Kids Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Healthy Skin and ARF Prevention BREATHMay 2021Increase in Body Mass Index in Children With HIV, Switched to Tenofovir Alafenamide Fumarate or Dolutegravir Containing Antiretroviral Regimens
Recent data indicate excessive weight gain in treatment-naive adults with HIV commenced on antiretroviral therapy (ART) regimens containing tenofovir alafenamide (TAF) or the integrase strand transfer inhibitors (INSTIs) dolutegravir (DTG) and bictegravir.
Published research Infectious Diseases Subsite: Wesfarmers Centre of Vaccines and Infectious Diseases Healthy Skin and ARF PreventionSeptember 2020Clinical Management of Staphylococcus aureus Bacteremia in Neonates, Children, and Adolescents
Staphylococcus aureus is a common cause of community and health care-associated bacteremia, with authors of recent studies estimating the incidence of S aureus bacteremia (SAB) in high-income countries between 8 and 26 per 100 000 children per year. Despite this, <300 children worldwide have ever been randomly assigned into clinical trials to assess the efficacy of treatment of SAB.
Published research Infectious Diseases Allergy & Infectious DiseasesJune 2020Progress towards a coordinated, national paediatric antimicrobial resistance surveillance programme
These data support that children are not just 'little adults' in the AMR era, and analyses by age group are important to detect differences in antibiotic susceptibility
Published research Infectious Diseases Group A Streptococcal & Rheumatic Heart Disease Infectious Diseases Epidemiology Healthy Skin and ARF PreventionOctober 2019A Survey of Infectious Diseases and Microbiology Clinicians in Australia and New Zealand About the Management of Staphylococcus aureus Bacteremia
Significant variation in practice, particularly for patients with a severe disease phenotype and antibiotic-resistant profile
Published research Infectious Diseases Healthy Skin and ARF PreventionJune 2019CASSETTE-clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation: Study protocol for a randomised controlled trial
This study will assess the effect of adjunctive clindamycin on patient-centred outcomes in severe, toxin-mediated S. aureus infections
Published research Infectious Diseases Healthy Skin and ARF Prevention