Honorary Research Associate
Dr Jessica Buck is using her unique training in both neuroscience and cancer to tackle the challenges of childhood brain cancer research. Jessica completed her Bachelor of Biomedical Science at the University of Newcastle in 2013. Following this she moved to the UK, where she completed her MSc in Neuroscience and a DPhil in Oncology in 2019 from the University of Oxford.
Jessica was supported by Charlie Perkins, Chevening, and Oxford Australia scholarships, and was awarded the 2019 Young Australian Achiever of the Year in the UK award for her research, leadership and sporting achievements. Jessica is currently a Forrest Research Fellow based at the Telethon Kids Institute and the University of Western Australia.
Cancer therapies inducing DNA damage
The induction of DNA damage has been employed as an anticancer strategy for more than 100years, first starting with the use of radiation to treat stomach cancer followed by the first uses of DNA-damaging chemotherapy to treat childhood leukemia.Children's Cancers Published research Brain Tumour ResearchApril 2021
Veliparib Is an Effective Radiosensitizing Agent in a Preclinical Model of Medulloblastoma
Medulloblastoma is the most common malignant childhood brain tumor, and 5-year overall survival rates are as low as 40% depending on molecular subtype, with new therapies critically important. As radiotherapy and chemotherapy act through the induction of DNA damage, the sensitization of cancer cells through the inhibition of DNA damage repair pathways is a potential therapeutic strategy.Children's Cancers Published research Brain Tumour Research Subsite: Cancer
Education and Qualifications