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        News & Events

        Perth researchers lead world-first clinical trial in Chile to stop COVID-19 outbreaks

        Perth researchers are leading an international clinical trial focused on preventing the spread of COVID-19 by testing the effectiveness of the drug interferon in reducing the infectiousness of people who contract the virus. ...

        Research

        Pragmatic Adaptive Trial for Respiratory Infection in Children (PATRIC) Clinical Registry protocol

        Acute respiratory infections (ARI) are the most common cause of paediatric hospitalisation. There is an urgent need to address ongoing critical knowledge gaps in ARI management. The Pragmatic Adaptive Trial for Respiratory Infections in Children (PATRIC) Clinical Registry will evaluate current treatments and outcomes for ARI in a variety of paediatric patient groups. ...

        Research

        Immunogenicity and Safety of Monovalent Acellular Pertussis Vaccine at Birth: A Randomized Clinical Trial

        The monovalent acellular pertussis vaccine is immunogenic and safe in neonates ...

        Research

        The ORVAC trial: A clinical trial of a third scheduled dose of Rotarix rotavirus vaccine in Australian Indigenous infants to improve protection against gastroenteritis

        We hypothesised that scheduling an additional (third) dose of oral human rotavirus vaccine for children aged 6 to <12 months would improve protection ...

        News & Events

        International clinical trial reduced lung inflammation in young kids with cystic fibrosis

        Promising results from an Australian-led clinical trial could drastically change the way we care for young children with cystic fibrosis (CF). ...

        News & Events

        Three-continent clinical trial aims to improve survival for aggressive kids’ brain cancer

        The Telethon Kids Institute and Perth Children’s Hospital will lead an international clinical trial of a novel drug combination they hope will increase cure rates for one of the most aggressive forms of childhood brain cancer. ...

        Research

        Continuous Glucose Monitoring Adherence: Lessons from a Clinical Trial to Predict Outpatient Behavior

        Continuous glucose monitoring adherence and patterns of use are individualized ...

        Research

        Improving clinical trial readiness to accelerate development of new therapeutics for Rett syndrome

        Rett syndrome is associated with severe functional impairments and many comorbidities, each in urgent need of treatments. Mutations in the MECP2 gene were identified as causing Rett syndrome in 1999. Over the past 20 years there has been an abundance of preclinical research with some studies leading to human clinical trials. ...

        Research

        The development of aboriginal brain injury coordinator positions: A culturally secure rehabilitation service initiative as part of a clinical trial

        Brain injury, resulting from stroke and traumatic brain injury, is a common occurrence in Australia, with Aboriginal people affected at a significant rate and impact felt by individuals, families and communities. Access to brain injury rehabilitation services for Aboriginal people is reported to be often limited, with very little support outside the hospital environment. ...

        Research

        Reporting Both Unadjusted and Adjusted Estimates Is Essential to the Interpretation of Randomized Clinical Trial Results - Reply

        Andrew Matt Whitehouse Watch and listen to Andrew Cooper AJ MC PhD BCA Marketing, BSc Statistics and Applied Statistics, PhD Angela Wright Bennett ...

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