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        Timeliness and factors associated with rotavirus vaccine uptake among Australian Aboriginal and non-Aboriginal children: A record linkage cohort study

        Aboriginal children are at greater risk of rotavirus disease than non-Aboriginal children and delayed vaccine receipt is substantially higher ...

        Research

        An introduction to clinical trial design

        This manuscript will give a brief overview of clinical trial design including the strengths and limitations of various approaches ...

        Research

        The Staphylococcus aureus Network Adaptive Platform Trial Protocol: New Tools for an Old Foe

        Staphylococcus aureus bloodstream (SAB) infection is a common and severe infectious disease, with a 90-day mortality of 15%-30%. Despite this, <3000 people have been randomized into clinical trials of treatments for SAB infection. ...

        Research

        Statistical analysis plan for the OPTIMUM study: optimising immunisation using mixed schedules, an adaptive randomised controlled trial of a mixed whole-cell/acellular pertussis vaccine schedule

        The purpose of this double-blind, randomised, controlled trial is to compare allergic outcomes in children following vaccination with acellular pertussis (aP) antigen (standard of care in Australia) given at 2 months of age versus whole cell pertussis (wP) in the infant vaccine schedule. ...

        Research

        Predictors of pneumococcal carriage and the effect of the 13-valent pneumococcal conjugate vaccination the Western Australian Aboriginal population

        The PCV7 was introduced to prevent IPD in WA Aboriginal people in 2001 to a lesser extent in older people. ...

        Research

        Dose-Banding of Intravenous Piperacillin-Tazobactam in Pediatric Surgical Inpatients

        Dosing errors are the most commonly reported medication error in children. Dosing is often prescribed per weight or based on body area. ...

        Research

        Impact of high coverage of monovalent human rotavirus vaccine on Emergency Department presentations for rotavirus gastroenteritis

        The program was associated with a substantial decline in rotavirus attributable non-admitted AGE presentations to ED among children aged <5 years. ...

        Research

        Effectiveness of Palivizumab in Preventing RSV Hospitalization in High Risk Children: A Real-World Perspective

        This review supports the recommended use of palivizumab for reducing RSV-associated hospitalisation rates in premature babies born at gestational age <33 weeks. ...

        Research

        Vaccine hesitancy, refusal and access barriers: The need for clarity in terminology

        We propose more precision in the term 'vaccine hesitancy' is needed particularly since much under-vaccination arises from factors related to access or pragmatics ...

        Research

        Assessment of on-time vaccination coverage in population subgroups: A record linkage cohort study

        On-time coverage of the 2-4-6 month schedule is only 50-60% across specific population subgroups representing a significant avoidable public health risk ...

        Research

        Paediatric antimicrobial stewardship and safe prescribing: An assessment of medical staff knowledge and behaviour

        Participants demonstrated a good understanding of safe prescribing and antimicrobial stewardship ...

        Research

        Comprehending the Health Informatics Spectrum: Grappling with System Entropy and Advancing Quality Clinical Research

        We outline three scenarios from across the health spectrum where issues with health informatics are exemplified. ...

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