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        Predicting the causative pathogen among children with osteomyelitis using Bayesian networks – improving antibiotic selection in clinical practice

        We have demonstrated the potential use of Bayesian Networks in improving antibiotic selection for children with osteomyelitis ...

        Research

        Choosing primary endpoints for clinical trials of health care interventions

        This narrative review describes the evolution, range and relative strengths and weaknesses of endpoints used in late phase trials ...

        Research

        Off-target effects of bacillus Calmette-Guerin vaccination on immune responses to SARS-CoV-2: implications for protection against severe COVID-19

        Because of its beneficial off-target effects against non-mycobacterial infectious diseases, bacillus Calmette-Guérin vaccination might be an accessible early intervention to boost protection against novel pathogens. Multiple epidemiological studies and randomised controlled trials are investigating the protective effect of BCG against coronavirus disease 2019 (COVID-19). ...

        Research

        The short term safety of COVID-19 vaccines in Australia: AusVaxSafety active surveillance, February – August 2021

        To assess the short term safety of the COVID-19 vaccines Comirnaty (Pfizer–BioNTech BNT162b2) and Vaxzevria (AstraZeneca ChAdOx1) in Australia. ...

        Research

        Acute haemoptysis, fever and abdominal pain in an adolescent from northern Australia

        Christopher Asha André Dr Anita Blyth Bowen Schultz Campbell CC AC AS AC MBBS (Hons) DCH FRACP FRCPA PhD BA MBBS DCH FRACP PhD GAICD MBChB, PhD, FRACP MBBS, DCH, PG DipPID, FRACP, NHMRC Postgraduate Scholarship Director, Wesfarmers Centre of ...

        Research

        Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015

        This paper reports the results from the safety surveillance of influenza vaccines in children in Australia, in 2015. ...

        Research

        Characterization of G2P[4] rotavirus strains causing outbreaks of gastroenteritis in the Northern Territory, Australia, in 1999, 2004 and 2009

        Outbreaks of rotavirus diarrhea cause a large disease burden in the Alice Springs region of the Northern Territory, Australia. ...

        Research

        Parental Tdap boosters and infant pertussis: a case-control study

        Case households had fewer immunized mothers (22% vs 32%) or fathers (20% vs 31%) but were more likely to include additional and older children. After... ...

        Research

        Assessing the effect of meningitis prevention and treatment.

        In high-income countries serious bacterial infections such as meningitis are uncommon, but their severity has led to prompt adoption of vaccines for... ...

        Research

        Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

        Combining elevated CRP with the presence or absence of clinical signs/ symptoms differentiates definite bacterial from presumed viral pneumonia better than CRP alone ...

        Research

        Protocol for Pertussis Immunisation and Food Allergy (PIFA): a case-control study of the association between pertussis vaccination in infancy

        We therefore speculate that removal of wP from the vaccine schedule contributed to the observed rise in IgE-mediated food allergy among Australian infants ...

        Research

        Association between respiratory syncytial viral disease and the subsequent risk of the first episode of severe asthma in different subgroups of high-risk Australian children: a whole-of-population-based cohort study

        To determine the contribution of RSV to the subsequent development of severe asthma in different subgroups of children at risk of severe RSV disease. ...

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