Browse study websites

Discover. Prevent. Cure.

Menu Fundraise Donate

    Recommended pages

      Do you mean

        49-60 of 66 results

        Refine research

        Research

        Respiratory viral infections and host responses; insights from genomics

        Review of the viral sensing pathways and organizing principles that govern the innate immune response to infection ...

        Research

        Bilateral murine tumor models for characterizing the response to immune checkpoint blockade

        This protocol describes bilateral murine tumor models that display a symmetrical yet dichotomous response to immune checkpoint blockade ...

        Research

        Rapid recruitment of CD14+ monocytes in experimentally induced allergic rhinitis in human subjects

        Mononuclear phagocyte population is directly involved in the production of proinflammatory chemokines that attract other immune cells ...

        Research

        Directing the future breakthroughs in immunotherapy: The importance of a holistic approach to the tumour microenvironment

        Immunotherapy has revolutionised the treatment of cancers by exploiting the immune system to eliminate tumour cells. Despite the impressive response in a proportion of patients, clinical benefit has been limited thus far. ...

        Research

        Airway IRF7hi versus IRF7lo molecular response patterns determine clinical phenotypes in children with acute wheezing

        We employed a systems biology approach to delineate upper airway gene network patterns underlying asthma exacerbation phenotypes in children. ...

        Research

        Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

        Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained ...

        Research

        QuantSeq. 3′ Sequencing combined with Salmon provides a fast, reliable approach for high throughput RNA expression analysis

        QuantSeq, coupled with a fast quantification method such as Salmon, should provide a viable alternative to traditional RNA-Seq in many applications ...

        Research

        Distinguishing benign from pathologic TH2 immunity in atopic children

        In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor ...

        Research

        Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivo

        The objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo. ...

        Research

        Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivo

        The objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo. ...

        Research

        Searching for a technology-driven acute rheumatic fever test: the START study protocol

        The absence of a diagnostic test for acute rheumatic fever (ARF) is a major impediment in managing this serious childhood condition. ARF is an autoimmune condition triggered by infection with group A Streptococcus. ...

        Research

        Innate immune activation occurs in acute food protein–induced enterocolitis syndrome reactions

        Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system ...

        Page 5 of 6