Advances in omics and specifically genomic technologies are increasingly transforming rare disease diagnosis. However, the benefits of these advances are disproportionately experienced within and between populations, with Indigenous populations frequently experiencing diagnostic and therapeutic inequities. The International Rare Disease Research Consortium (IRDiRC) multi-stakeholder partnership has been advancing toward the vision of all people living with a rare disease receiving an accurate diagnosis, care, and available therapy within 1 year of coming to medical attention. In order to further progress toward this vision, IRDiRC has created a taskforce to explore the access barriers to diagnosis of rare genetic diseases faced by Indigenous peoples, with a view of developing recommendations to overcome them. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

The prevalence of IgE binding to the group 15 and 18 house dust mite (HDM) allergens of the Dermatophagoides species... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• October 2012

The aim of this study was to examine the relationship between nasopharyngeal pneumococcal colonization in early life and the development of T cell responses. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012

Aim was to standardize the names given to the antigens (allergens) that caused IgE-mediated allergies in humans ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

We recruited age- and sex-matched Chinese immigrants living in Western Australia for less than 6 months (newly arrived, n = 22) or more than 5 years. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• April 2018

Pneumococcal surface protein A is immunogenic and natural anti-PspA immune responses are acquired through exposure and develop with age ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• August 2016

Our results indicate a dissociation between the antibody and T-cell responses to rhinoviruses ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• November 2016

Measures of allergic sensitization and therapeutic strategies could be optimized with knowledge of Der p 2 variants ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

This study analysed the IgE binding patterns caused by house dust mite allergens in scabies endemic communities in Australia. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• December 2015

This comprehensive review provides an introduction to immunological hypersensitivity, discusses the sensitisation of T-cell lineages. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• November 2015

Delayed development of antibodies to S. pneumoniae in infancy is associated with the development of atopy and asthma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• July 2015