The re-emergence of scarlet fever poses a new global public health threat. The capacity of North-East Asian serotype M12 (emm12) Streptococcus pyogenes (group A Streptococcus, GAS) to cause scarlet fever has been linked epidemiologically to the presence of novel prophages ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

Infections by RV species A and C are the most common causes of exacerbations of asthma and a major cause of exacerbations of other respiratory disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• March 2018

A recent systematic review of 5 randomized clinical trials, found that early egg introduction was associated with reduced egg allergy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• May 2017

Pat Belinda Holt Hales PG BJ PhD, DSc, FRCPath, FRCPI, FAA BSc (Hons) PhD Emeritus Honorary Researcher Senior Manager, Research Platforms Patrick.Holt@telethonkids.org.au belinda.hales@telethonkids.org.au Emeritus Honorary Researcher Senior Manager ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• September 2010

The allergenic load of house dust mite allergy is largely constituted by a few proteins with a hierarchical pattern of allergenicity. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• June 2015

Lymphocyte recruitment to peripheral tissues is fundamental for immune surveillance and homeostasis, but the chemokines and chemokine receptors responsible... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

The development of food allergy has been reported to be related with the changes in the gut microbiome, however the specific microbe associated with the pathogenesis of food allergy remains elusive. This study aimed to comprehensively characterize the gut microbiome and identify individual or group gut microbes relating to food-allergy using 16S rRNA gene sequencing with network analysis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

The Human Phenotype Ontology was launched in 2008 to provide a comprehensive logical standard to describe and computationally analyze phenotypic abnormalities found in human disease. The HPO is now a worldwide standard for phenotype exchange. The HPO has grown steadily since its inception due to considerable contributions from clinical experts and researchers from a diverse range of disciplines. Here, we present recent major extensions of the HPO for neurology, nephrology, immunology, pulmonology, newborn screening, and other areas. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Asthma exacerbations are associated with human rhinovirus (HRV) infections, and more severe exacerbations are associated with HRV-C. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014

Human rhinoviruses (HRV) are associated with upper and lower respiratory illnesses, including severe infections causing hospitalization in both children... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• August 2013

House dust mites (HDM) are a globally important source of allergen responsible for the sensitization of more than 50% of allergic patients. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• July 2013

More than 50% of allergic patients have house dust mite (HDM) allergy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• July 2012