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        Influenza hospitalizations in Australian children

        NIP has seen poor vaccine impact, related to recent vaccine safety concerns. ...

        Research

        Influenza

        Influenza (commonly known as the flu) is caused by a highly contagious virus spread mainly through coughing and sneezing. An annual flu vaccination is the most effective way to prevent flu outbreaks. ...

        Research

        BCG vaccination to reduce the impact of COVID-19 in healthcare workers: Protocol for a randomised controlled trial (BRACE trial)

        BCG vaccination modulates immune responses to unrelated pathogens. This off-target effect could reduce the impact of emerging pathogens. As a readily available, inexpensive intervention that has a well-established safety profile, BCG is a good candidate for protecting healthcare workers (HCWs) and other vulnerable groups against COVID-19. ...

        Research

        Influenza hospitalizations in Australian children 2010–2019: The impact of medical comorbidities on outcomes, vaccine coverage, and effectiveness

        Children with comorbidities are at greater risk of severe influenza outcomes compared with healthy children. In Australia, influenza vaccination was funded for those with comorbidities from 2010 and all children aged <5 years from 2018. Influenza vaccine coverage remains inadequate in children with and without comorbidities. ...

        Research

        Association between vaccination status, symptom identification and healthcare use: Implications for test negative design observational studies

        To test the internal validity of the test-negative design (TND) by investigating associations between maternal influenza vaccination, and new virus detection episodes (VDEs), acute respiratory illness, and healthcare visits in their children. ...

        Research

        Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2017: the Influenza Complications Alert Network (FluCAN)

        This report summarises the epidemiology of hospitalisations with laboratory-confirmed influenza during the 2017 influenza season ...

        Research

        Timeliness of signal detection for adverse events following influenza vaccination in young children: a simulation case study

        Active vaccine safety surveillance leading to rapid detection of a safety signal would likely have resulted in earlier suspension of Fluvax from the vaccination programme ...

        Research

        Comparative Postmarket Safety Profile of Adjuvanted and High-Dose Influenza Vaccines in Individuals 65 Years or Older

        The findings of this postmarketing assessment of the safety of 2 new enhanced influenza vaccines support confidence in ongoing vaccine use ...

        Research

        The impact of influenza infection on young children, their family and the health care system

        Influenza infection in young children has a significant impact on medication use, absenteeism and the use of health care service ...

        Research

        Active surveillance of 2017 seasonal influenza vaccine safety: An observational cohort study of individuals aged 6 months and older in Australia

        AusVaxSafety surveillance demonstrated comparable and expected safety outcomes for the 2017 quadrivalent inactivated influenza vaccine brands used in Australia ...

        Research

        Does a 10-valent pneumococcal-Haemophilus influenzae protein D conjugate vaccine prevent respiratory exacerbations in children

        Our study will be the first to assess vaccine efficacy targeting H. influenzae in children with recurrent PBB, CSLD and bronchiectasis. ...

        Research

        Protective anti-outer membrane protein immunity against Pasteurella pneumotropica infection of mice

        The proteins examined were the homologues of the P4, P6, P26, and D15 proteins of Haemophilus influenzae. ...

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