Whereas asthma was rare in the late 1800s and early 1900s, the marked increase in its incidence and prevalence since the 1960s points to substantial gene ×... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• September 2014

In healthy individuals, deep inspirations (DIs) taken prior to a bronchial challenge reduce the bronchoconstrictor response, which is termed... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• October 2012

We aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• April 2012

The objective of this study was to examine the influence of viral respiratory infection (VRI) on treatment response in acute asthma in children. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

Chronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• August 2011

Asthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• May 2011

With the emergence of allergic and autoimmune diseases in populations that have started to transit to a western lifestyle, there has been an increasing... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• December 2010

IgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• July 2010

Early immunological influences on asthma development: opportunities for early intervention ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• January 2010

This study investigated the potential role of ST2 in children with acute asthma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2009
• March 2009

Deborah Pat Strickland Holt DH PG PhD PhD, DSc, FRCPath, FRCPI, FAA Program Head, Immunobiology and Immunotherapeutic Program Emeritus Honorary Researcher Deb.Strickland@telethonkids.org.au Patrick.Holt@telethonkids.org.au Program Head, ...

• 1. Telethon Kids Institute
• Our research
• Past teams
• Human Immunology

Ingrid Pat Laing Holt IL PG BSc PhD PhD, DSc, FRCPath, FRCPI, FAA Honorary Research Fellow Emeritus Honorary Researcher 6319 1828 Ingrid.laing@telethonkids.org.au@hotmail.cmo Patrick.Holt@telethonkids.org.au Honorary Research Fellow Emeritus ...

• 1. Telethon Kids Institute
• Projects