Food allergy affects up to 10% of Australian infants. It was hypothesized that if parents follow the Australasian Society of Clinical Immunology and Allergy guidelines, Australian food allergy rates may stabilize or decline. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023

To reduce peanut allergy prevalence, infant feeding guidelines now recommend introducing peanuts in an age-appropriate form (such as peanut butter) as part of complementary feeding. However, due to a lack of randomized trial evidence, most infant feeding and food allergy prevention guidelines do not include tree nuts. The aims of this trial were to determine safety and feasibility of dosage consumption recommendations for infant cashew nut spread introduction. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

Clinical studies supported by immunological data indicate early life intervention strategies to be promising in reducing the growing global burden of food allergies. The events that predispose to food allergy, including the induction of allergen-specific immune responses, appear to be initiated early in development. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

The immunological changes underpinning acquisition of remission (also called sustained unresponsiveness) following food immunotherapy remain poorly defined. Limited access to effective therapies and biosamples from treatment responders has prevented progress. Probiotic peanut oral immunotherapy is highly effective at inducing remission, providing an opportunity to investigate immune changes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

We systematically reviewed the literature on the genetic basis of food allergy, identifying areas for further investigation ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• September 2019

Maternal supplementation with 900 mg of ω-3 LCPUFA did not change the progression of IgE-mediated allergic disease symptoms or sensitization ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

Elevated egg-specific Th2 cytokine responses were established prior to egg ingestion at 4months and were not significantly altered by introduction of egg ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Antioxidant intakes in pregnancy may influence fetal immune programming and the risk of allergic disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• November 2012

We therefore speculate that removal of wP from the vaccine schedule contributed to the observed rise in IgE-mediated food allergy among Australian infants ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

Prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10% and reaches 20-30% in those with an allergic... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

To show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE allergy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• February 2012

This study examined whether maternal and/or fetal folate status in pregnancy is associated with infant allergic outcomes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012