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        Challenges to curing primary brain tumours

        The seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment in brain tumours ...

        Research

        The Australian and New Zealand Children's Haematology/Oncology Group Biobanking Network

        The ANZCHOG-BN was developed to improve and streamline access to high quality pediatric and adolescent/young adult cancer biospecimens for cancer research ...

        Research

        Use of bevacizumab as a single agent or in adjunct with traditional chemotherapy regimens in children with unresectable or progressive low-grade glioma

        Bevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity ...

        Research

        Diffuse Intrinsic Pontine Glioma

        This chapter summarizes recent advances in diffuse intrinsic pontine glioma and potential novel therapies ...

        Research

        Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG Registry

        These findings provide a compelling argument for efforts to reduce exposure of the brainstem in the treatment of medulloblastoma ...

        Research

        The case for DNA methylation based molecular profiling to improve diagnostic accuracy for central nervous system embryonal tumors (not otherwise specified) in adults

        We report the case of a 45-year-old woman who was diagnosed with a NOS based on immunohistochemical analysis of the patient's tumor at diagnosis. ...

        Research

        A novel technique of serial biopsy in mouse brain tumour models

        Here we describe a method by which serial biopsy can be used to validate response to dacomitinib treatment in vivo using a mouse glioblastoma model ...

        Research

        Folate pathway gene polymorphisms and risk of childhood brain tumors: Results from an Australian case-control study

        Recent research suggests that maternal folic acid supplementation is associated with a reduced risk of childhood brain tumors (CBT); polymorphisms in folate... ...

        Research

        Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas

        The outcome for children with high-grade gliomas (HGG) remains dismal, with a 2-year survival rate of only 10% to 30%. ...

        Research

        Bacillus Cereus Bacteremia and Multiple Brain Abscesses During Acute Lymphoblastic Leukemia Induction Therapy

        Bacillus cereus can cause serious infections in immunosuppressed patients. This population may be susceptible to B. cereus pneumonia, bacteremia, cellulitis,... ...

        Research

        Meningiomas in children and adolescents: a meta-analysis of individual patient data

        The epidemiological, prognostic, and therapeutic features of child and adolescent meningioma are poorly defined... ...

        Research

        Polymorphisms associated with normal memory variation also affect memory impairment in schizophrenia

        Neurocognitive dysfunction is a core feature of schizophrenia with particularly prominent deficits in verbal episodic memory. ...

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