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        Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised children

        We aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked. ...

        Research

        Airway Epithelial Cells Condition Dendritic Cells to Express Multiple Immune Surveillance Genes

        AEC-conditioned DC showed selective upregulation of chemokines that recruit Th1 cells, but minimal change in chemokines linked to Th2 cell recruitment. ...

        Research

        Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specific

        Chronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear ...

        Research

        Epithelial-dendritic cell interactions in allergic disorders

        Airway epithelial cells act through multiple mechanisms to function as an important component of the pulmonary defence strategy that is crucial... ...

        Research

        Structural and IgE binding analyses of recombinant Der p 2 expressed from the hosts Escherichia coli and Pichia pastoris

        Authors: Tanyaratsrisakul S, Malainual N, Jirapongsananuruk O, Smith WA, Thomas WR, Piboonpocanun S. Authors notes: Int Arch Allergy Immunol. 2010;151(3):190-8. Epub 2009 Sep 29. Keywords: structural, IgE binding analyses, recombinant Der p 2, ...

        Research

        Early immunological influences on asthma development: opportunities for early intervention

        Early immunological influences on asthma development: opportunities for early intervention ...

        Research

        Acute viral bronchiolitis in infants and young children

        Deborah Pat Strickland Holt DH PG PhD PhD, DSc, FRCPath, FRCPI, FAA Program Head, Immunobiology and Immunotherapeutic Program Emeritus Honorary Researcher Deb.Strickland@telethonkids.org.au Patrick.Holt@telethonkids.org.au Program Head, ...

        Research

        Vitamin D over the first decade and susceptibility to childhood allergy and asthma

        We aimed to research relationships between 25(OH)D levels from birth to 10 y/o and susceptibility to allergic sensitization, respiratory issues and asthma. ...

        Research

        Elucidation of pathways driving asthma pathogenesis: Development of a systems-level analytic strategy

        Whereas asthma was rare in the late 1800s and early 1900s, the marked increase in its incidence and prevalence since the 1960s points to substantial gene ×... ...

        Research

        Asthma and allergies in a cohort of adolescents conceived with ART

        Research question: Are asthma and allergies more common in adolescents conceived with assisted reproductive technologies (ART) compared with adolescents conceived without? ...

        Research

        Protection against severe infant lower respiratory tract infections by immune training: Mechanistic studies

        Results from recent clinical studies suggest potential efficacy of immune training (IT)-based approaches for protection against severe lower respiratory tract infections in infants, but underlying mechanisms are unclear. ...

        Research

        Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school-aged children

        The expression pattern of FcεRI on DC and basophils differentiates asthmatic from non-asthmatic atopic children ...

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