To investigate changes in trapped air volume and distribution over time and compare computed tomography (CT) with pulmonary function tests for determining... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• March 2015

We hypothesized that allergic inflammation decreases the level of circulating 25(OH)D and tested this using a mice model of house dust mite (HDM) induced... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• November 2014

Our findings provide new insight into the molecular mechanisms operative at baseline in the airway mucosa in atopic asthmatic with natural aeroallergen exposure ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

The present study investigated whether lung function measured by forced oscillation technique would be impaired in the presence of infection,... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• September 2015

Evidence suggests consumption of a Mediterranean diet (MD) can positively impact both maternal and offspring health, potentially mediated by a beneficial effect on inflammatory pathways. We aimed to apply metabolic profiling of serum and urine samples to assess differences between women who were stratified into high and low alignment to a MD throughout pregnancy and investigate the relationship of the diet to inflammatory markers.   ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

Differential cell counts is a challenging task when applying computer vision algorithms to pathology. Existing approaches to train cell recognition require high availability of multi-class segmentation and/or bounding box annotations and suffer in performance when objects are tightly clustered. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

In this translational review, the mechanisms, roles, and impact of epithelial-mesenchymal transition in chronic lung diseases are discussed ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

The COVID-19 pandemic introduced challenges to everyone in society but particularly so to every aspect of medical practice. It is bewildering how quickly the profession has had to respond to rapidly changing clinical landscape. Our well-established methods involve collecting and analyzing data to generate an evidence base which is then disseminated and implemented into routine clinical practice. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020

Acinar ventilation inhomogeneity measured by single-breath washout was not associated with structural lung disease on CT ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• May 2019

Our data associates IL-1α with early structural lung damage in CF and suggests this pathway as a novel anti-inflammatory target ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018