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        Research

        High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis

        High dose vitamin D supplementation is associated with a shift to a more inflammatory faecal microbiome and increased susceptibility to colitis ...

        Research

        Ultraviolet radiation, Vitamin D and the development of obesity, metabolic syndrome and type-2 diabetes

        Emerging findings suggest a protective role for ultraviolet radiation (UVR) and sun exposure in reducing the development of obesity and cardiometabolic dysfunction, but more epidemiological and clinical research is required that focuses on measuring the direct associations and effects of exposure to UVR in humans. ...

        Research

        Are there differences in immune responses following delivery of vaccines through acutely or chronically sun-exposed compared with sun-unexposed skin?

        The review provides the basis for further research into the effects of acute and chronic UV radiation exposure on skin cells in the context of vaccination ...

        Research

        Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study

        This genome-wide association study (GWAS) utilises data from the Western Australian Pregnancy Cohort (Raine) Study for 25-hydroxyvitamin D (25(OH)D) levels... ...

        Research

        Vitamin D deficiency at 16 to 20 weeks' gestation is associated with impaired lung function and asthma at 6 years of age

        This paper examines whether a Vitamin D deficiency during pregnancy affects the child's lung function predisposition towards lung disease such as asthma. ...

        Research

        Low vitamin D levels are associated with symptoms of depression in young adult males

        Results from studies examining associations between serum 25-hydroxyvitamin D (25(OH)D) concentrations and depressive symptoms are equivocal. ...

        Research

        Characterization of regulatory dendritic cells differentiated from the bone marrow of UV-irradiated mice

        In summary, UV-BMDCs do not express the classical phenotypic or gene expression properties of DCs reported by others as 'regulatory' or 'tolerogenic'. ...

        Research

        Vitamin D supplementation, moderate sun exposure, and control of immune diseases

        There is considerable debate about the benefits of vitamin D supplementation for multiple sclerosis, allergic asthma, and type 1 diabetes. ...

        Research

        Responsiveness of the human airway in vitro during deep inspiration and tidal oscillation

        In healthy individuals, deep inspiration produces bronchodilation and reduced airway responsiveness, which may be a response of the airway wall to mechanical... ...

        Research

        UV inhibits allergic airways disease in mice by reducing effector CD4 T cells

        Shelley Prue Gorman Hart S PH BSc (Hons) PhD BSc (Hons) MSc PhD Honorary Research Associate Head, Inflammation shelley.gorman@telethonkids.org.au ...

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