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        Research

        Clinical significance of circulating microRNAs as markers in detecting and predicting congenital heart defects in children

        In this study, we aimed to investigate the usefulness of miRNAs as biomarkers in diagnosing and predicting children with congenital heart defects (CHD), particularly in the context of multiple subtypes of CHD. ...

        Research

        International consensus (ICON) on: Clinical consequences of mite hypersensitivity, a global problem

        The objectives of this document are to highlight aspects of mite biology that are clinically relevant and to update the current knowledge on mite allergens ...

        Research

        Randomized controlled trial of early regular egg intake to prevent egg allergy

        We aimed to determine whether regular consumption of egg protein from 4-6 month old reduced the risk of IgE-mediated egg allergy in infants without eczema. ...

        Research

        IgG Responses to Pneumococcal and Haemophilus Influenzae Protein Antigens Are Not Impaired in Children with a History of Recurrent Acute Otitis Media

        Vaccines including conserved antigens from Streptococcus pneumoniae & nontypeable Haemophilus influenzae have the potential to reduce of otitis media. ...

        Research

        The anti-inflammatory effects of interleukin-4 are not mediated by suppressor of cytokine signalling-1 (SOCS1)

        Authors: Woodward EA, Prêle CM, Nicholson SE, Kolesnik TB, Hart PH. Authors notes: Immunology. 2010 Sep;131(1):118-27. Epub 2010 Apr 6. Keywords: ...

        Research

        Th2-associated immunity to bacteria in asthma in teenagers and susceptibility to asthma

        Bacterial colonisation of the airways is associated with increased risk of childhood asthma ...

        Research

        Molecular characterization of Der p 10: A diagnostic marker for broad sensitization in house dust mite allergy

        Tropomyosins represent clinically relevant seafood allergens but the role of mite tropomyosin ...

        Research

        CD4 allergen tetramers

        The introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties... ...

        Research

        Immune Responses to Allergens in Atopic Disease: Considerations for Bioinformatics

        Allergies are mediated by several immunological mechanisms that make different contributions in different patients. ...

        Research

        Distinguishing benign from pathologic TH2 immunity in atopic children

        In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor ...

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