Respiratory syncytial virus is the second most common cause of infant mortality and a major cause of morbidity and mortality in older adults (aged >60 years). Efforts to develop a respiratory syncytial virus vaccine or immunoprophylaxis remain highly active. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

Despite substantial declines since 2000, lower respiratory infections (LRIs), diarrhoeal diseases, and malaria remain among the leading causes of nonfatal and fatal disease burden for children under 5 years of age (under 5), primarily in sub-Saharan Africa. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

An effective disease surveillance system is critical for early detection and response to disease epidemics. This study aimed to assess the capacity to manage and utilize disease surveillance data and implement an intervention to improve data analysis and use at the district level in Tanzania. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

Campylobacter jejuni is a bacterial pathogen recognised as a major cause of foodborne illness worldwide. While Campylobacter jejuni generally does not grow outside its host, it can survive outside of the host long enough to pose a health concern. This review presents an up-to-date description and evaluation of biological, mathematical, and statistical approaches used to understand the behaviour of this foodborne pathogen and suggests future avenues which can be explored. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

David Burgner, Nick de Klerk, Kim Carter   Infection is the leading cause of global child mortality and morbidity, and in Australia the commonest ...

• 1. Telethon Kids Institute
• Our research
• Expertise and technologies
• Bioinformatics

Melinda Judge, Erica Parker, Denise Naniche, Lucia Pastor, Kim W Carter, Denise Anderson, Peter LeSouëf.   This is the largest acute HIV cohort ...

• 1. Telethon Kids Institute
• Our research
• Expertise and technologies
• Bioinformatics

Respiratory viruses, particularly respiratory syncytial virus and human metapneumovirus, are major contributors to pneumonia in Australian children ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

Group A Streptococcus (Strep A) is an important cause of mortality and morbidity globally. This bacterium is responsible for a range of different infections and post-infectious sequelae. Summarising the current knowledge of Strep A transmission to humans will address gaps in the evidence and inform prevention and control strategies. The objective of this study is to evaluate the modes of transmission and attack rates of group A streptococcal infection in human populations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

We have demonstrated the potential use of Bayesian Networks in improving antibiotic selection for children with osteomyelitis ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• July 2020

Respiratory syncytial virus is pervasive across multiple severity levels and diagnoses. Vaccines targeting children <3 months must be prioritized ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020