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        Research

        Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children

        Food allergy (FA) affects 2%-10% of US children and is a growing clinical and public health problem. ...

        Research

        Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants

        The purpose of this article is to highlight emerging evidence for existing allergy prevention guidelines regarding potential benefits of supporting early... ...

        Research

        Early introduction of food reduces food allergy – Pro and Con

        When an infant is developmentally ready, a variety of nutritious foods should be introduced including the ‘more allergenic’ foods during infancy ...

        Research

        Early life innate immune signatures of persistent food allergy

        Early life innate immune dysfunction may represent a key immunological driver and predictor of persistent food allergy in childhood ...

        Research

        Gene-vitamin D interactions on food sensitization: A prospective birth cohort study

        It has been hypothesized that vitamin D deficiency (VDD) contributes to the development of food sensitization (FS) and then food allergy. ...

        News & Events

        Telethon Kids Institute researchers share in TPCHRF funding

        Eight Telethon Kids Institute researchers are among those who have received grant funding from the Telethon-Perth Children’s Hospital Research Fund (TPCHRF). ...

        News & Events

        Cow’s milk protein allergies on the rise in our kids

        Up to three out of every 100 babies develop cow's milk protein allergy (CMPA) in their first year of life – and this number appears to be on the rise ...

        News & Events

        ORIGINS Project reaches key milestone

        The ORIGINS Project, a collaboration between Telethon Kids and the Joondalup Health Campus, has achieved a major milestone – recruiting its 1000th family. ...

        Research

        Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapy

        Peanut allergy is the the most common cause of life-threatening food-induced anaphylaxis. There is currently no effective long-term treatment. There is a pressing need for definitive treatments that improve the quality of life and prevent fatalities. Allergen oral immunotherapy (OIT) is a promising approach, which is effective at inducing desensitisation; however, OIT has a limited ability to induce sustained unresponsiveness (SU). ...

        Research

        Dysfunctional gut microbiome networks in childhood ige‐mediated food allergy

        The development of food allergy has been reported to be related with the changes in the gut microbiome, however the specific microbe associated with the pathogenesis of food allergy remains elusive. This study aimed to comprehensively characterize the gut microbiome and identify individual or group gut microbes relating to food-allergy using 16S rRNA gene sequencing with network analysis. ...

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