High risk for virus-induced asthma exacerbations in children is associated with an IRF7lo immunophenotype, but the underlying mechanisms are unclear. Here, we applied a Systems Biology approach to an animal model comprising rat strains manifesting high versus low susceptibility to experimental asthma, induced by virus/allergen coexposure, to elucidate the mechanism(s)-of-action of the high-risk asthma immunophenotype. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021

This review focuses on smokers and nonsmokers and evaluates the most recent data regarding the potential health effects of e-cigarettes ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

There are a multitude of ways that, with respect to early-life exposures and health, electronic nicotine delivery systems are a cause for concern ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

These data provide proof of concept supporting the rationale for developing transplacental immune reprogramming approaches for primary disease prevention ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

Canola biodiesel exhaust exposure elicits inflammation and reduces viability of human epithelial cell cultures in vitro when compared with ULSD exhaust exposure ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

This study aimed to determine whether chronic, low-dose exposure to geogenic particulate matter <10μm diameter (PM10) exacerbates viral infections of the... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• November 2015

In utero exposure to arsenic via drinking water increases the risk of lower respiratory tract infections during infancy and mortality from bronchiectasis in... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• February 2013

Males are generally more susceptible to respiratory infections; however, there are few data on the physiological responses to such infections in males and... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• March 2011

Biodiesel is created through the transesterification of fats/oils and its usage is increasing worldwide as global warming concerns increase. Biodiesel fuel properties change depending on the feedstock used to create it. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• April 2022

Treatment strategies for juvenile idiopathic arthritis (JIA) have shifted significantly over the last 20 years. We examined the effect of the introduction of government-subsidised TNF inhibitor (TNFi) treatment on incident hospitalisation for JIA. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023