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        Research

        Deregulated expression of connective tissue growth factor is linked to poor outcome in human cancer

        Connective tissue growth factor (CTGF/CCN2) has long been associated with human cancers. The role it plays in these neoplasms is diverse and tumour specific. ...

        Research

        Childhood craniopharyngioma: 20-year institutional experience in Western Australia

        Although neurocognitive, psychological and behavioural problems were noted for some patients during medical review, only 20% of patients were formally assessed. ...

        Research

        A novel, palatable paediatric oral formulation of midazolam: Pharmacokinetics, tolerability, efficacy and safety

        We conclude that the novel chocolate-based formulation of midazolam provides improved tolerability while remaining efficacious ...

        Research

        New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment

        We provide evidence that targeting leukemia-induced bone loss is a therapeutic strategy for pre-B ALL ...

        Research

        Primary central nervous system lymphoma: Initial features, outcome, and late effects in 75 children and adolescents

        Children with Primary Central Nervous System Lymphoma and no immunodeficiency have a good outcome ...

        Research

        Optimized peripheral blood progenitor cell mobilization for autologous hematopoietic cell transplantation in children with high-risk and refractory malignancies

        Our approach to hematopoietic progenitor cells mobilization resulted in highly effective HPC harvest in children and adolescents with high-risk cancers ...

        Research

        Targeting DYRK1A: a key player in Down syndrome Leukaemogenesis

        Sébastien Malinge SM PhD Laboratory Head, Translational Genomics in Leukaemia, Ursula Kees Fellow (CCRF), Cancer Council WA Fellow (CCWA), Senior ...

        Research

        Therapeutic opportunities from dissecting the pre-B leukaemia bone marrow microenvironment

        Laurence Rishi Sury Sébastien Cheung Kotecha Malinge LC RS SM BPharm (Hons) MBA PhD MB ChB (Hons) MRCPCH FRACP PhD PhD Co-Head, Leukaemia ...

        Leukaemia Translational Research

        The main aim of our Leukaemia Translational Research Team is to test innovative therapeutic approaches, with a focus on clinical translation of this knowledge, to improve the outcomes of children suffering from leukaemia. ...

        Research

        Cancer Program

        Listed are all Telethon Kids Institute research teams involved in our Cancer Program. This program sits under the Chronic and Severe Diseases research theme. ...

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