Allergen specific immunotherapy aims to subvert or divert immune responses to allergens to ones that do not cause immunological hypersensitivities. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• September 2017

The aim of this study was to identify features of innate, cell-mediated and humoral immunity that may increase susceptibility to respiratory infections in... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• August 2014

This paper summarizes updates of allergen names approved at the meetings of the IUIS Allergen Nomenclature Sub-Committee in 2011 through 2013. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014

Advances in omics and specifically genomic technologies are increasingly transforming rare disease diagnosis. However, the benefits of these advances are disproportionately experienced within and between populations, with Indigenous populations frequently experiencing diagnostic and therapeutic inequities. The International Rare Disease Research Consortium (IRDiRC) multi-stakeholder partnership has been advancing toward the vision of all people living with a rare disease receiving an accurate diagnosis, care, and available therapy within 1 year of coming to medical attention. In order to further progress toward this vision, IRDiRC has created a taskforce to explore the access barriers to diagnosis of rare genetic diseases faced by Indigenous peoples, with a view of developing recommendations to overcome them. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

Neonates have heightened susceptibility to infections. The biological mechanisms are incompletely understood but thought to be related to age-specific adaptations in immunity due to resource constraints during immune system development and growth. We present here an extended analysis of our proteomics study of peripheral blood-plasma from a study of healthy full-term newborns delivered vaginally, collected at the day of birth and on day of life (DOL) 1, 3, or 7, to cover the first week of life. The plasma proteome was characterized by LC-MS using our established 96-well plate format plasma proteomics platform. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

Safe, highly curative, short course, direct acting antiviral (DAA) therapies are now available to treat chronic hepatitis C. DAA therapy is freely available to all adults chronically infected with the hepatitis C virus (HCV) in Australia. If left untreated, hepatitis C may lead to progressive hepatic fibrosis, cirrhosis and hepatocellular carcinoma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

Fel d 7 is a common allergen in a Swedish cat-sensitized population that cross-reacts with Can f 1 ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• October 2016

In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Allergies are mediated by several immunological mechanisms that make different contributions in different patients. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Tropomyosins represent clinically relevant seafood allergens but the role of mite tropomyosin ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• October 2011