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        Research

        Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability

        HRV-1B infection directly alters human airway epithelial TJ expression leading to increased epithelial permeability potentially via antiviral response of IL-15 ...

        Research

        Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrity

        In disease settings, vitamin D may be important for maintaining optimal lung epithelial integrity and suppressing inflammation, but less is known of its effects prior to disease onset. ...

        Research

        The effect of TNF treatment uptake on incident hospital admission in Western Australia

        Treatment strategies for juvenile idiopathic arthritis (JIA) have shifted significantly over the last 20 years. We examined the effect of the introduction of government-subsidised TNF inhibitor (TNFi) treatment on incident hospitalisation for JIA. ...

        Research

        Toxicity of different biodiesel exhausts in primary human airway epithelial cells grown at air-liquid interface

        Biodiesel is created through the transesterification of fats/oils and its usage is increasing worldwide as global warming concerns increase. Biodiesel fuel properties change depending on the feedstock used to create it. ...

        Research

        Early life rhinovirus infection exacerbates house-dust-mite induced lung disease more severely in female mice

        Early life rhinovirus infection influences the development of house-dust-mite induced lung disease in female, but not male mice ...

        Research

        Biodiesel exhaust-induced cytotoxicity and proinflammatory mediator production in human airway epithelial cells

        Our results show that canola biodiesel exhaust exposure elicits inflammation and reduces viability of human epithelial cell cultures in vitro when compared... ...

        Research

        The effect of diesel exhaust exposure on blood-brain barrier integrity and function in a murine model

        Epidemiological studies indicate that exposure to diesel exhaust (DE) is associated with vascular-based disorders. ...

        Research

        Emerging Early Life Environmental Exposures and Lung Development

        In this review article we systematically summarize the evidence for an impact on lung development of 1) maternal ingestion of arsenic contaminated drinking... ...

        Research

        Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma control

        The hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation. ...

        Research

        Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort study

        Authors: von Ungern-Sternberg BS, Boda K, Chambers NA, Rebmann C, Johnson C, Sly PD, Habre W. Authors notes: |Lancet. 2010 Sep 4;376(9743):773-83. ...

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