This letter addresses the recommendations by the American Thoracic Society & European Respiratory Society in 2005, that patients must wait 15-60mins between... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• February 2015

This report summarizes techniques available for ventilated and spontaneously breathing infants and children in the ICU ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• February 2016

Cystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• June 2013

The aim of this study was to document the likely interpretative effects of changing from commonly used current spirometry reference equations to the GLI2012... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• August 2013

Preterm infants have immature control of breathing and impaired pulmonary gas exchange. We hypothesized that infants with bronchopulmonary dysplasia (BPD) have a blunted ventilatory response and peripheral oxygen saturation (SpO2 ) instability during a hypoxic challenge. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• February 2023

Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 participants, we identified 1,020 independent association signals implicating 559 genes supported by ≥2 criteria from a systematic variant-to-gene mapping framework. These genes were enriched in 29 pathways. Individual variants showed heterogeneity across ancestries, age and smoking groups, and collectively as a genetic risk score showed strong association with COPD across ancestry groups. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023

We aimed to quantify the diagnostic utility of mannitol challenge testing for asthma in a community cohort and a symptomatic wheezing subset of this cohort. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• May 2017

Our findings provide new insight into the molecular mechanisms operative at baseline in the airway mucosa in atopic asthmatic with natural aeroallergen exposure ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

Assessment of airway hyperresponsiveness are valuable tools to understand and to monitor airway function and to characterise the underlying asthma phenotype to guide therapy ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

We conclude that the novel chocolate-based formulation of midazolam provides improved tolerability while remaining efficacious ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018