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        Research

        Genome-Wide Analysis of Genetic Risk Factors for Rheumatic Heart Disease in Aboriginal Australians Provides Support for Pathogenic Molecular Mimicry

        Rheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers proinflammatory cardiac valve-reactive T cells. ...

        Research

        An atlas of human long non-coding RNAs with accurate 5′ ends

        Combining these findings with conservation data, we identify 19,175 potentially functional lncRNAs in the human genome. ...

        Research

        In vitro drug susceptibility of two strains of the wildlife trypanosome, Trypanosoma copemani: A comparison with Trypanosoma cruzi

        Compared the in vitro susceptibility of two strains of Trypanosoma copemani and one strain of T. cruzi against drugs that show trypanocidal activity ...

        Research

        Reference genotype and exome data from an Australian Aboriginal population for health-based research

        This data set provides a useful reference point for genomic studies on Aboriginal Australians ...

        Research

        Candidate gene analysis supports a role for polymorphisms at TCF7L2 as risk factors for type 2 diabetes in Sudan

        Jenefer Sarra Blackwell Jamieson JM SE BSc with First Class Honours, PhD, DSc, FMedSci, FAA BSc (Hons) MSc PhD Head, Genetics & Health Senior ...

        Research

        Immunogenetics of Parasitic and Bacterial Disease

        Here we focus on more recent well-powered genome-wide association studies, including malaria, leprosy, tuberculosis, and visceral leishmaniasis ...

        Research

        Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children

        Identified an association between polymorphisms in a long intergenic non-coding RNA (lincRNA) gene (AC011288.2) and pneumococcal bacteremia ...

        Research

        Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer.

        disease-deconvolution" identified associations between the parasite-brain interactions and epilepsy, movement disorders, Alzheimer's disease, and cancer. ...

        Research

        No simple answers for the Finnish and Russian Karelia allergy contrast: Methylation of CD14 gene

        The methylation variation in the promoter region of CD14 gene did not explain the asthma and allergy contrast between Finnish and Russian Karelian children ...

        Research

        Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study

        This genome-wide association study (GWAS) utilises data from the Western Australian Pregnancy Cohort (Raine) Study for 25-hydroxyvitamin D (25(OH)D) levels... ...

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