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        The time lag prior to the rise in glucose requirements to maintain stable glycaemia during moderate exercise in a fasted insulinaemic state is of short duration

        There is a 20-min low exogenous glucose demand period during which the glucose requirements to maintain stable glycaemia do not increase during moderate exercise ...

        Research

        ISPAD Clinical Practice Consensus Guidelines 2018: Exercise in children and adolescents with diabetes

        Promotion of regular physical activity is an integral part of diabetes care delivery and health care providers should promote this message at every available opportunity ...

        Research

        Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

        We find that DNA methylation in neonatal blood is associated with birthweight, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation ...

        Research

        The glycaemic benefits of a very-low-carbohydrate ketogenic diet in adults with Type 1 diabetes mellitus may be opposed by increased hypoglycaemia risk and dyslipidaemia

        This study provides the first evidence that, ketogenic diets in adults with Type 1 diabetes are associated with excellent HbA1c levels and little glycaemic variability ...

        Research

        Effect of 6 months of hybrid closed-loop insulin delivery in adults with type 1 diabetes: A randomised controlled trial protocol

        Determine the effectiveness of 6 months' closed-loop compared with manually determined insulin dosing on time-in-target glucose range in adults with type 1 diabetes ...

        Research

        Acute hyperglycaemia does not alter nitric oxide-mediated microvascular function in the skin of adolescents with type 1 diabetes

        Impact of an acute bout of hyperglycaemia on nitric oxide (NO)-mediated microvascular function in the skin of adolescents with type 1 diabetes ...

        Research

        Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studies

        Pregnancy and birth cohorts have been utilised extensively to investigate the developmental origins of health and disease, particularly in relation to... ...

        Research

        Antecedent hypoglycaemia does not diminish the glycaemia-increasing effect and glucoregulatory responses of a 10 s sprint in people with type 1 diabetes

        The purpose of this study was to investigate whether antecedent hypoglycaemia impairs the glycaemia-raising effect of a 10 s sprint in individuals with type... ...

        Research

        Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood.

        This study identifies widespread DNA methylation changes in whole blood associated with childhood obesity. ...

        Research

        Analysis of glucose responses to automated insulin suspension with sensor-augmented pump therapy

        The advent of sensor-augmented pump therapy with a low-glucose suspend (LGS) function. ...

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