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        Research

        Early Nutrition as a Major Determinant of 'Immune Health': Implications for Allergy, Obesity and Other Noncommunicable Diseases

        A better understanding of nutritional programming of immune health may lead to dietary strategies that reduce the burden of many inflammatory diseases ...

        Research

        Physician training programs significantly improve diagnosis in cases coded as anaphylaxis over time: A major factor compounding time-trend data?

        Recent studies based on hospital admissions have reported a significant increase in anaphylaxis prevalence. ...

        Research

        Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studies

        Pregnancy and birth cohorts have been utilised extensively to investigate the developmental origins of health and disease, particularly in relation to... ...

        Research

        Elevated IL-5 and IL-13 responses to egg proteins predate the introduction of egg in solid foods in infants with eczema

        Elevated egg-specific Th2 cytokine responses were established prior to egg ingestion at 4months and were not significantly altered by introduction of egg ...

        Research

        World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Prebiotics

        Develop evidence-based recommendations about the use of prebiotics in the prevention of allergy ...

        Research

        The role of PKCzeta in cord blood T-cell maturation towards Th1 cytokine profile and its epigenetic regulation by fish oil

        Here, we present evidence that there are two major control points to explain the immunodeficiency in CB T-cells, leading to a decreased IFNy synthesis. ...

        Research

        Influence of maternal obesity on the long-term health of offspring

        Including immediate implications for pregnancy complications, increasing evidence implicates maternal obesity having a major impact on long term child health. ...

        Research

        Pre- and probiotics for allergy prevention: time to revisit recommendations?

        We discuss how the choice of probiotic strains, timing and duration of administration can critically influence the outcome due to different effects on immune modulation and gut microbiota composition ...

        Research

        Autism spectrum disorder in children born preterm: Role of exposure to perinatal inflammation

        This review aims to summarise and evaluate the potential mechanisms and evidence for the role of prenatal infection on the central nervous system, and how it... ...

        Research

        “Food faddists and pseudoscientists!”: Reflections on the history of resistance to ultra-processed foods

        The term 'ultra-processed food' emerged in the 1980s, mostly used in reference to highly-processed convenience foods and snacks, often energy-dense, poor in nutrients, and inclusive of various synthetic additives such as emulsifiers, colors, artificial sweeteners, and/or flavor enhancers. ...

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