Studies addressing the ontogeny of the innate immune system in early life have reported mainly on Toll-like receptor (TLR) responses in infants living in... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• May 2012

Cow's milk allergy is rare in exclusively breastfed infants. To support the continuation of breastfeeding an infant after diagnosis with a cow's milk allergy, it is critical to examine the evidence for and against any form of cow's milk elimination diet for lactating mothers. In this narrative review, we highlight the lack of high-quality evidence, hence subsequent controversy, regarding whether the minuscule quantities of cow's milk proteins detectable in human milk cause infant cow's milk allergy symptoms. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• November 2023

In this review, we describe both the mechanisms and the therapeutic evidence from preclinical and clinical studies exploring the role of prebiotics in allergy prevention ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

Cutaneous squamous cell carcinoma is a significant cause of morbidity for immunosuppressed patients such as organ transplant recipients; however, histological parameters which predict the likelihood of tumor progression are typically based on general population studies in which immunosuppressed patients represent only a small fraction of cases.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• April 2024

Previous reports suggested that food proteins present in human milk (HM) may trigger symptoms in allergic children during breastfeeding, but existing evidence has never been reviewed systematically. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022

Improving maternal gut health in pregnancy and lactation is a potential strategy to improve immune and metabolic health in offspring and curtail the rising rates of inflammatory diseases linked to alterations in gut microbiota. Here, we investigate the effects of a maternal prebiotic supplement (galacto-oligosaccharides and fructo-oligosaccharides), ingested daily from <21 weeks' gestation to six months' post-partum, in a double-blinded, randomised placebo-controlled trial.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• March 2024

Early infancy oral vitamin D supplementation does not appear to reduce the development of early childhood allergic disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

This paper discusses the rising prevalence of allergic disease in children. This review article considers recent findings in the field of paediatric immune... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• October 2015

Reliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• August 2014

This review article examines the evidence of the impact of in utero and postnatal vitamin D exposure on allergy risk in childhood ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• December 2014