Team
Computational Biology projects
Featured Research
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
An atlas of active enhancers across human cell types and tissues
A promoter-level mammalian expression atlas
An integrated encyclopedia of DNA elements in the human genome
Landscape of transcription in human cells
Reports and Findings
Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows
Systematic comparison of recovered cell types and their transcriptional profiles across the workflows has highlighted protocol-specific biase
Published research Computational BiologyAssessing the unified airway hypothesis in children via transcriptional profiling of the airway epithelium
Upper and lower airways are conserved in their transcriptional composition, and variations associated with disease are present in both nasal and tracheal epithelium
Published research Systems Immunology Computational Biology Airway Epithelial Research P4 Respiratory Health for KidsBilateral murine tumor models for characterizing the response to immune checkpoint blockade
This protocol describes bilateral murine tumor models that display a symmetrical yet dichotomous response to immune checkpoint blockade
Children's Cancers Published research Systems Immunology Computational Biology Sarcoma Translational ResearchReference exome data for Australian Aboriginal populations to support health-based research
Our data set provides a useful reference point for genomic studies on Aboriginal Australians
Published research Aboriginal Health Group A Streptococcal & Rheumatic Heart Disease Computational Biology Genetics and Health