Head, Epigenetics
BSc, BHlthSc, PhD
Dr Sam Buckberry is a genome biologist and bioinformatician who works within Professor Alex Brown's Indigenous Genomics group. His research focuses on improving the long-term health of Indigenous Australian populations by developing new community-specific knowledge and methods in precision medicine. Sam's approach integrates cutting-edge genomics and data science techniques with epidemiology and public health to improve chronic disease prediction, prevention, and treatment.
Sam has broad experience in molecular biology, bioinformatics, research computing and data science. He enjoys developing custom analysis frameworks for complex biological questions and data types. Sam has published widely in epigenetics and genomics, including high profile papers in journals including Cell Stem Cell, Nature and Nature Neuroscience.
Sam was an NHMRC postdoctoral research fellow at The University of Western Australia between 2016-19 and held a WA Department of Health Merit Award Grant for 2020-21.
Sam was awarded the 2019 Raine Research Prize for the best biomedical research paper by an early career researcher in WA. In 2020, he was one of four finalists for the Woodside Early Career Scientist of the Year as part of the WA Premier's Science Awards.
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Publications
August 2023
Transient naive reprogramming corrects hiPS cells functionally and epigenetically
Cells undergo a major epigenome reconfiguration when reprogrammed to human induced pluripotent stem cells (hiPS cells). However, the epigenomes of hiPS cells and human embryonic stem (hES) cells differ significantly, which affects hiPS cell function. These differences include epigenetic memory and aberrations that emerge during reprogramming, for which the mechanisms remain unknown.
Published research Indigenous Genomics -
Education and Qualifications
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Awards/Honours
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Active Collaborations