Team
Computational Biology projects
Featured Research
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
An atlas of active enhancers across human cell types and tissues
A promoter-level mammalian expression atlas
An integrated encyclopedia of DNA elements in the human genome
Landscape of transcription in human cells
Reports and Findings
Elucidating the interaction of CF airway epithelial cells and rhinovirus: Using the host-pathogen relationship to identify future therapeutic strategies
A better understanding of the innate immune responses by CF airway epithelial cells is needed to identify why viral infections are more severe in CF
Cystic Fibrosis Published research Computational Biology Airway Epithelial Research P4 Respiratory Health for KidsConserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuli
We obtain a set of 57 candidate immediate early genes possessing promoters that consistently drive a rapid but transient increase in expression over time
Published research Computational BiologyArylsulphatase A Pseudodeficiency (ARSA-PD), hypertension and chronic renal disease in Aboriginal Australians
Traits associated with CVD, CRD and T2D in Aboriginal Australians provide novel insight into function of Arylsulphatase A Pseudodeficiency variants
Published research Aboriginal Health Diabetes and Obesity Computational Biology Genetics and HealthDiscovery of Transcription Factors Novel to Mouse Cerebellar Granule Cell Development Through Laser-Capture Microdissection
This study provides an initial insight into the TFs of cerebellar granule cells that might be important for development
Published research Computational Biology